<?xml version="1.0" encoding="UTF-8"?>
<rss version="2.0">
	<channel>
		<title>
        <![CDATA[Latest posts for the topic "The prenatal environment - new FAS study" recent IAN discussions]]>
    </title>
		<link>http://kki.qorvis.com/forum/posts/list/7.page</link>
		<description><![CDATA[Latest messages posted in the topic "The prenatal environment - new FAS study"]]></description>
		<generator>JForum - http://www.jforum.net</generator>
			<item>
				<title>The prenatal environment - new FAS study</title>
				<description><![CDATA[ Fetal Alcohol Syndrome has been identified as being associated with ASD risk:

http://www.ncbi.nlm.nih.gov/pubmed/9344050?

Classical twin study design assumes an equal prenatal envornment and twin studies in ASD have reported a 60% concordance rate in identical twins and 0% concordance rate in fraternal twins.

http://www.ncbi.nlm.nih.gov/pubmed/7792363?

The prenatal environment in twin pregnancies differs between identical and fraternal twins. 2/3's of identical twins share the same prenatal environment (same placenta) while 1/3 of identical twins and all fraternal twins develop in seperate placentas.

Could concordance rates in ASD classical twin studies be better explained by differences in the prenatal environment?

A new study suggests that the answer is yes. Gerari et al examined the placenta of a pair of fraternal twins who had been heavily exposed prenatally to alcohol. A series of guinea pig littermates who were prenatally exposed to alcohol was  included in the study as a control.

The authors found that one fraternal twin had high amounts of alcohol in the placental tissue while the co-twin had no level of alcohol in the placental tissue.

http://www.ncbi.nlm.nih.gov/pubmed/19127948?

Classical twin studies which assume an equal prenatal environment may have overstated the magnitude of the genetic component in ASD.]]></description>
				<guid isPermaLink="true">http://kki.qorvis.com/forum/posts/list/351.page#1815</guid>
				<link>http://kki.qorvis.com/forum/posts/list/351.page#1815</link>
				<pubDate><![CDATA[Mon, November 30, 2009]]> GMT</pubDate>
				<author><![CDATA[ RAJ]]></author>
			</item>
	</channel>
</rss>

